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KMID : 1161420160190060593
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Journal of Medicinal Food
2016 Volume.19 No. 6 p.593 ~ p.600
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Coptis chinensis Polysaccharides Inhibit Advanced Glycation End Product Formation
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Yang Ye
Li Yun
Yin Dengke
Chen Song
Gao Xiangdong
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Abstract
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Coptis chinensis Franch (Huanglian) is commonly used to treat diabetes in China. In this study, the effects of the C. chinensis Franch polysaccharides (CCP) on advanced glycation end product (AGE) formation in vitro and in streptozotocin-induced diabetic mice were investigated. CCP significantly inhibited all the three periods of nonenzymatic protein glycation in vitro, including Amadori product, dicarbonyl compound, and AGE formation (P?
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KEYWORD
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advanced glycation end products, Coptis chinensis Franch, diabetes, polysaccharide
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